Anthony Frudakis was born in 1953 at Bellows Falls, Vermont into a professional art family. Although he grew up in an artistic environment he was allowed to pursue his own interests. In 1973 he became an apprentice in his father's studio where he compiled a portfolio of work, earning him several scholarships to study at the Pennsylvania Academy of the Fine Arts in Philadelphia. After earning many accolades at the Academy, Frudakis went on to travel and study in London, Paris, Florence, Rome and Athens.

In 1976, Anthony Frudakis taught and served as Academy Director for the Frudakis Academy of the Fine Arts in Philadelphia. He also taught sculpture and drawing at Stockton State College at Pomona, New Jersey. The following years saw his work capturing the John Spring Art Founder Award and the Walter Lantz Youth Prize from the National Sculpture Society. Frudakis also exhibited at the National Academy of Design.

After Frudakis' work was receiving regional acclaim, he then set up a studio in New York City where he began to accept international commissions. During this time, he also taught sculpture at the Fashion Institute of Technology. From work produced at his New York studio, his sculpture was awarded several awards by National Sculpture Society including a Gold Medal, the Maurice B. Hexter Award, the Walter and Michael Lantz Prize, and the prestigious Gloria Medal for a meritorious body of work by a Young Sculptor.

As his technique matured, the sculptor began to produce work on a larger scale. A monumental bas-relief depicting the winged horse, Pegasus, was created in 1983 for the Atlantic County Library in Hammonton, New Jersey. In 1986 Frudakis received commissions from two Atlantic City hotels, Summer, a monumental bronze group of a young, bathing suit-clad couple, running on the beach, was created for the Tropicana Hotel & Casino. A life-size Otter Fountain in cold cast bronze was placed in the health spa at Bally's Park Palace Hotel & Casino.

In 1986 he was awarded the Leonard Meiselman Prize at the annual exhibition of the National Sculpture Society for Floating Nude. Two years later a Mother and Child, installed in cold cast bronze, was commissioned by the Atlantic City Day Nursery. In 1989, for the Cape May Court House, Anthony Frudakis designed a monumental bas-relief entitled Justice. His bronze portrait bust of the physician and medical researcher, Dr. Charles Drew, was unveiled at the opening of Drew Court, a housing project built by the Atlantic City Improvement Authority.

Frudakis is a fellow of the National Sculpture Society and has served on the Atlantic City Fine Arts Commission. Currently, he is sculptor in residence at Hillsdale College.